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DATA SHEET
Primencin® Injectable solution 7.5% Ciprofloxacin Kind Antibiotic Formulation Injectable Presentations Glass bottle 20, 100 and 250 mL Registry REG. SAGARPA Q -2083- 046
  • FORMULA
     INGREDIENTS: Guaranteed analysis Ciprofloxacin (as Ciprofloxacin Hydrochloride) 75 mg. Automob the cbp 1 mL INERT INGREDIENTS Inert ingredients up to 100%
  • DESCRIPTION
    Pharmacokinetics After intramuscular administration Primecin diffuses rapidly achieving therapeutic levels in fluids and tissues (lung primarily tissue), where it enters the cells to exert their bactericidal action takes place both in the stage of rapid cell growth, and stationary phase with MICs (MIC90) between 0.01 to 2.0 mcg / mL; so its bactericidal action is fast start, in most cases, at concentrations 2-4 times only bacteriostatic. MODE OF ACTION The bactericidal effect of Primecin is based on their ability to inhibit the enzymatic action of topoisomerase, acting on the microbial DNA: Primecin has rapid bactericidal action by inhibiting the DNA gyrase (topoisomerase II) is the enzyme responsible super curl DNA and transcription and cellular replication, thus causing a lethal effect on the microbial DNA. Primecin acts quickly both in the resting phase and multiplication (inhibition of bacterial gyrase), while other antibiotics, act only in the period of multiplication. Action spectrum activity Primecin comprises a wide range of microorganisms: Gram negative: Actinobacillus pleuropneumoniae Pasteurella multocida (Haemophilus) Pasteurella (Mannheimia) haemolytica Bacteroides spp Pseudomonas sp Bordetella bronchiseptica Salmonella spp Escherichia coli Shigella spp Haemophilus spp Campylobacter spp Gram positive: Clostridium spp Corynebacterium Erysipelothrix rhusipathiae Listeria monocytogenes Staphylococcus aureus Staphylococcus spp Streptococcus spp Mycoplasmas Mycoplasma hyopneumoniae Mycoplasma hyorhinis Mycoplasma bovis Mycoplasma gallisepticum Mycoplasma synoviae
  • DOSE
    Bovines 1 mL per 30 kg, equivalent to 2.5 mg of ciprofloxacin per kg. In pigs 1 mL per 20 kg, equivalent to 3.75 mg of ciprofloxacin per kg. Route of Administration: Given by deep intramuscular injection.
  • WARNINGS
    Do not use this product 5 days before slaughter of animals intended for human consumption. Not consume milk treated animals until after 48 hours of the last treatment. PRECAUTIONS In pigs not apply more than 5 mL at the same site. In calves not apply more than 10 mL in the same place. In cattle apply no more than 20 mL in the same place. Keep out of reach of children Store at shade and in a cool place.

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